This study analyzed the concentrations of toxic (Cr, Co, Cu, etc.) and radiotoxic (U, Th) heavy metals (HMs) in 40 commercial cereal samples consumed in Türkiye by using an energy dispersive X-ray fluorescence spectrometer. Health risks caused by ingestion of cereal samples were assessed using the hazard index (HI), annual effective dose (EEff), and the excess lifetime cancer risk (LCR) models. The average concentrations (mg/kg dry weight) of HMs analyzed in the samples were 2.7 (Cr), 6.4 (Co), 7.9 (Cu), 49.8 (Fe), 49.4 (Mn), 7.6 (Ni), 40.4 (Zn), 1.0 (U), and 1.4 (Th). Wheat and maize showed HI >1, indicating potential concern for consumers. The total annual effective dose exceeded global averages primarily due to Th in cereal samples. Findings highlight the need for monitoring and consumer guidance.
Adam, A.A., Sackey, L.N.A., & Ofori, L.A., 2022. Risk assessment of heavy metals concentration in cereals and legumes sold in the Tamale Aboabo market, Ghana. Heliyon 8, 1–6.
Alengebawy, A., Abdelkhalek, S.T., Qureshi, S.R., & Wang, M.-Q., 2021. Heavy metals and pesticides toxicity in agricultural soil and plants: ecological risks and human health implications. Toxics 9(42), 1–33.
Ali, H., Khan, E., Ilahi, I., 2019. Environmental chemistry and ecotoxicology of hazardous heavy metals: environmental persistence, toxicity, and bioaccumulation. J. Chem. 2019, 1–15.
Ali, M.H.H., & Al-Qahtani, K.K., 2012. Assessment of some heavy metals in vegetables, cereals and fruits in Saudi Arabian markets. Egypt. J. Aquat. Res. 38, 31–37.
Altamemi, R., Turhan, Ş. & Kurnaz, A., 2021. Natural and anthropogenic radioactivity in some vegetables and fruits commonly consumed in the Western Black Sea region of Turkey. Radiochim. Acta 109(12), 935–942.
Altıkulaç, A, & Turhan, Ş., 2023. Assessment of the levels of potentially toxic elements contained in natural bentonites collected from quarries in Turkey. ACS Omega 8(23), 20797–20986.
Amarloei, A., Nourmoradi, H., Nazmara, S., Heidari, M., Mohammadi-Moghadam, F., & Mazloomi, S., 2025. Toxic heavy metals of agricultural products in developing countries and its human health risk assessment: A study from Iran. Heliyon 11(1), 1–9.
Anjum, S., & Rana, S., 2023. Chapter 8 - Impact of environmental pollutants on agriculture and food system, Editor(s): Satish Chandra Pandey, Veni Pande, Diksha Sati, Mukesh Samant, In Developments in Applied Microbiology and Biotechnology, Advanced Microbial Techniques in Agriculture, Environment, and Health Management, Academic Press, pages: 133–151.
Baz, S.S., & Alamoudi, Z.M., 2017. Naturally occurring radioactive nuclides from cereal grains, legumes and some foodstuffs consumed in Saudi Arabia. Life Sci. J. 14(7), 1–5.
Bedoya-Perales, N., Maus, D., Pumi, G., Dantas, S.V.A., & Ferreira, S.L.C., 2025. Health risk assessment from heavy metals in crops grown and marketed by family farmers in the mining region of Moquegua, Peru. Food Res. Int. 217, 1–9.
Briffa, J., Sinagra, E., Blundell, R., 2020. Heavy metal pollution in the environment and their toxicological effects on humans. Heliyon 6(9), 1–26.
Brizio, P., Benedetto, A., Squadrone, S., Curcio, A., Pellegrino, M., Ferrero, M., & Abete, M. C., 2016. Heavy metals and essential elements in Italian cereals. Food Addit. Contam. Part B 9(4), 261–267.
Cengiz, G.B., & Çağlar, İ., 2021. determination of the natural radioactivity distribution and consumption effective dose rate of cereal crops in Ardahan province, Turkey. J. Sci. Rep. A, 047, 174–183.
Chasapis, C.T., Ntoupa, P.S.A., Spiliopoulou, C.A., & Stefanidou, M.E., 2020. Recent aspects of the effects of zinc on human health. Arch. Toxicol. 94(5), 1443–1460.
Ercilla-Montserrat, M., Muñoz, P., Montero, J.I., Gabarrell, X., & Rieradevall, J., 2018. A study on air quality and heavy metals content of urban food produced in a Mediterranean city (Barcelona). J. Clean. Prod. 195, 385–395.
Getu, A., Seid, Y., & Asrade, B., 2022. Determination of the level of heavy metals in the selected cereals from Debre Markos local market, Amhara region, Ethiopia. Int. J. Anal. Chem. 2022, 1–7.
Hasan, G.M.M.A., Das, A.K., & Satter, M.A., 2022. Accumulation of heavy metals in rice (Oryza sativa. L) grains cultivated in three major industrial areas of Bangladesh. J. Environ. Public Health 2022, 1–8.
Hosseini, T., Fathivand, A.A., Barati, H., & Karimi, M., 2006. Assessment of radionuclides in imported foodstuffs in Iran. Iran. J. Radiat. Res. 4, 149–153.
Ikem, A., Odumosu, P.O., & Udousoro, I., 2023. Elemental composition of cereal grains and the contribution to the dietary intake in the Nigerian population. J. Food Compos. Anal. 118, 1–13.
ICRP, 2012. International Commission on Radiological Protection (ICRU). Compendium of Dose Coefficients based on ICRP Publication 60. ICRP Publication 119. Ann. ICRP 41(Suppl.) Published by Elsevier Ltd.
ICRP, 1990. International Commission on Radiological Protection (ICRU). Recommendations of the International Commission on radiological protection. Oxford: Pergamon Press; 1990; (Annals of the ICRP; 21(1–3), ICRP Publication; 60).
Jibiri, N.N., Farai, I.P., & Alausa, S.K., 2007. Activity concentrations of 226Ra, 228Th, and 40K in different food crops from a high background radiation area in Bitsichi, Jos Plateau, Nigeria. Radiat. Environ. Biophy. 46, 53–59.
Karapınar, H.S., 2023. Composition of some trace elements in wheat plant and soil. Anat. J. Bot. 7(1), 40–45.
Kerketta, A., Kumar, H., Powell, M.A. Sahoo, P.K., Kapoor, H.S., & Mittal, S., 2023. Trace element occurrence in vegetable and cereal crops from parts of Asia: a meta-data analysis of crop-wise differences. Curr. Pollut. Rep. 9, 1–21.
Kulshreshtha, D., Ganguly, J., & Jog, M., 2021. Manganese and movement disorders: A review. J. Mov. Disord. 14(2), 93–102.
Kumar, U., Singh, P.K., Kumar, I., & Sharma, R.K., 2025. Heavy metal accumulation, yield and health risk assessment of wheat crop grown in contaminated soil amended with bioash for sustainable agriculture. J. Food Compos. Anal. 139, 1–15.
Lefebvre, P., Gourgiotis, A., Mangeret, A., Sabatier, P., Le Pape, P., Diez, O., Louvat, P., Menguy, N., Merrot, P., Baya, C. and Zebracki, M., 2021. Diagenetic formation of uranium-silica polymers in lake sediments over 3,300 years. Proc. Natl. Acad. Sci. 118(4), 1–19.
Lenka, P., Sahoo, S.K., Mohapatra, S., Patra, A.C., Dubey, J.S., Vidyasagar, D., Tripathi, R.M., & Puranik, V.D., 2013. Ingestion dose from 238U, 232Th, 226Ra, 40K and 137Cs in cereals, pulses and drinking water to adult population in a high background radiation area, Odisha, India. Radiat. Prot. Dosim. 153(3), 328–333.
Leyssens, L., Vinck, B., Van Der Straeten, C., Wuyts, F., & Maes, L., 2017. Cobalt toxicity in humans-A review of the potential sources and systemic health effects. Toxicology 387, 43–56.
Lindahl P., Maquet A., Hult M., Gasparro J., Marissens G., González de Orduña R. Natural radi Lindahl, P., Maquet, A., Hult, M., Gasparro, J., Marissens, G., & González de Orduña, R., 2011. Natural radioactivity in winter wheat from organic and conventional agricultural systems. J. Environ. Radioact. 102, 163–169.
Liu, P., Zhang, Y., Feng, N., Zhu, M., & Tian, J., 2020. Potentially toxic element (PTE) levels in maize, soil, and irrigation water and health risks through maize consumption in northern Ningxia, China. BMC Public Health 20(1), 1–13.
Luo, W., Zhang, Y., Wei, P., Sun, C., 2024. Assessment of heavy metal(loid) pollution and human health risks associated with a mineral (Zn, Cu, and Sn ores) processing plant in Yunnan, Southwest China. Minerals 14, 1–17.
Ma, M., Wang, R., Xu, L., Xu, M., & Liu, S., 2020. Emerging health risks and underlying toxicological mechanisms of uranium contamination: Lessons from the past two decades. Environ. Int. 145, 1–15.
Madomguia, D., Basokdou, G.B., Appoline Isabelle, K.W., Dongo, P.K., Nya, E., & Togouet, S.H.Z., 2024. Accumulation of heavy metals in maga-pouss rice fields (far-north region, cameroon) and transfer to rice grains. Agric. Sci. 15, 311–326.
Miletić, A., Lučić, M., & Onjia, A., 2023. Exposure factors in health risk assessment of heavy metal(loid)s in soil and sediment. Metals 13(7), 1–28.
Naeem, M., Gill, R., Gill, S.S., Singh, K., Sofo, A., & Tuteja, N., 2023. Editorial: Emerging contaminants and their effect on agricultural crops. Front. Plant Sci. 14, 1–7.
Nematollahi, A., Abdi, L., Abdi-Moghadam, Z., Fakhri, Y., Borzoei, M., Tajdar oranj, B., Thai, V.M., Linh, N.T.T., & Khaneghah, A.M., 2021. The concentration of potentially toxic elements (PTEs) in sausages: a systematic review and meta-analysis study. Environ. Sci. Pollut. Res. 28, 55186–55201.
Obasi N.A., Obasi S.E., Ajala L.O., Aloh G.O., Aloke C., Ogundapo S.S., & Onyeji G.N., 2022. Nutrient interaction and health risk assessment of cereal grains on Nigerian's markets. J. Food Qual. Hazards Control. 9, 137–146.
Oudh, A.J.A., Kadhim, M.J.H., Abdul-Hussein, A.K., & Al-Khafaji, Z., 2025. Natural and anthropogenic radionuclides concentration and risk assessment in legumes and grains, which provides in a basket foodstuff in Iraq country. Nucl. Eng. Sci. 10(1), 1–13.
Ozturk, A., & Arici, O.K., 2021. Carcinogenic-potential ecological risk assessment of soils and wheat in the eastern region of Konya (Turkey). Environ. Sci. Pollut. Res. 28(12), 15471–15484.
Popoola, F.A., Isola, O.B., Fakeye, O.D., Owolabi, T.A., Sanyaolu, M.E., Owoyemi, S.I., & Elijah, I.O., 2024. Examination of medicinal plants for radionuclide absorption and their health implications. Pollution 10(2), 700–711.
R Core Team R, 2023. A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https://www.R-project.org/
Rafaqat, S., Aslam, A., Riaz, U., Alsudays, U.M., Javied, S., Hassan, N., Saleh, M.A., Alamer, K.H., & Uz Zaman, Q., 2025. Health risk assessment of heavy metal accumulation in rice grains cultivated by industrial effluents. Appl. Environ. Soil Sci. 2025, 1–14.
Salih, N.F., 2018. Determination of natural radioactivity and radiological hazards of 226Ra, 232Th, and 40K in the grains available at Penang markets, Malaysia, using high-purity germanium detector. The Scientific Journal of Koya University VI, 71–77.
Sultan, D., Turhan, Ş., Kurnaz, A., Hançerlioğulları, A., Kamberli, A., & Emeksizoğlu, B., 2020. Investigation of natural radionuclide and essential metal contents of ancient wheat einkorn (Triticum monococcum L.) grown in Turkey. Radiochim. Acta 108(12), 999–1007.
TatahMentan, M., Nyachoti, S., Okwori, O.F., & Godebo, T.R., 2023. Elemental composition of rice and lentils from various countries: A probabilistic risk assessment of multiple life stages. J. Food Compos. Anal. 115, 1–14.
Tawalbeh, A.A., Abumurad, K.M., Samat, S.B., & Yasir, M.S., 2011. A study of natural radionuclide activities and radiation hazard index in some grains consumed in Jordan. Malay. J. Anal. Sci. 15, 61–69.
Taylor, A.A., Tsuji, J.S., Garry, M.R., McArdle, M.E., Goodfellow, W.L. Jr, Adams, W.J., & Menzie, C.A., 2020. Critical Review of Exposure and Effects: Implications for Setting Regulatory Health Criteria for Ingested Copper. Environ. Manag. 65(1), 131–159.
Tchounwou, P. B., Yedjou, C. G., Patlolla, A. K., & Sutton, D. J., 2012. Heavy metal toxicity and the environment. Exp. Suppl. 101, 133–164.
Tegegne, W.A., 2015. Assessment of heavy metal concentration in selected cereals collected from local markets of Ambo city, Ethiopia. J. Cereals and Oilseeds 6(2), 8–13.
Tekin, M., Cengiz, M.F., Abbasov, M., Aksoy, A., Canci, H., & Akar, T., 2018. Comparison of some mineral nutrients and vitamins in advanced hulled wheat lines. Cereal Chem. 95, 436–444.
TÜİK, 2025. Türk Standardları Enstitüsü (Turkish Statistical Institute) (TÜİK). Bitkisel Ürün Denge Tabloları; "Tahıllar ve Diğer Bitkisel Ürünler", 2000/'01-2023/'24. Web page: https://data.tuik.gov.tr/Bulten/Index?p=Bitkisel-Uretim-Istatistikleri-2025-53939
Turhan, Ş., 2020. Evaluation of agricultural soil radiotoxic element pollution around a lignite-burning thermal power plant. Radiochim. Acta 108(1), 77–85.
Turhan, Ş., Akata, I., Kumru, E., & Altuner, E.M., 2024. Heavy metal analysis of wild edible mushrooms grown in Türkiye and assessment of possible carcinogenic and non-carcinogenic risk. J. Food Compos. Anal. 135, 1–14.
Turhan, Ş., 2025. Health risk assessment caused by external and internal exposure to radiation dose from naturally occurring radioactive materials in outdoor dust. Environ. Geochem. Health, 47, 1–13.
TSI, 2025. Turkish Statistical Institute (TSI). Production of cereals and other crops. Web page: https://data.tuik.gov.tr/Bulten/Index?p=Bitkisel-Uretim-Istatistikleri-2024-53447.
UNSCEAR, 2000. United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). Sources and Effects of Ionizing Radiation. Vol. I. Sources. Report to the General Assembly with Scientific Annexes, United Nations, New York.
USEPA, 1989. United States Environmental Protection Agency (USEPA). Risk assessment guidance for superfund. Volume I: Human health evaluation manual (Part A), EPA/540/1–89/002, Washington, DC.
Van Grieken, R., Markowicz. A., 2001. Handbook of X-Ray Spectrometry. CRC press.
Vasilachi, I.C., Stoleru, V., & Gavrilescu, M., 2023. Analysis of heavy metal impacts on cereal crop growth and development in contaminated soils. Agriculture 13, 1–50.
Wang, P., Wang, X., Wang, H., & Zhang, G., 2024. Health risk assessment of heavy metals from grains and grain products in Gansu Province, China, 2012-2020. J. Food Compos. Anal. 125, 1–11.
Yadav, P.K., & Singh, A.K., 2022. A review of iron overload in beta-thalassemia major, and a discussion on alternative potent iron chelation targets. Plasmatology 16, 1–9.